Abiozen’s Formulation Development services are strategically designed to enhance the therapeutic performance, safety, and market viability of pharmaceutical compounds. Our multidisciplinary formulation scientists leverage deep domain expertise and cutting-edge technologies to deliver optimized drug products tailored to each molecule’s specific requirements. We support every phase from pre-formulation through to clinical readiness and scale-up, ensuring a streamlined, regulatory-aligned path to commercialization.

Enhancing Solubility and Bioavailability
One of the most critical challenges in formulation science is poor aqueous solubility, which can severely limit a drug’s absorption and efficacy. At Abiozen, we employ innovative techniques such as nanotechnology, amorphous solid dispersions, and lipid-based delivery systems to significantly enhance solubility and bioavailability. These advanced approaches ensure that even poorly soluble or complex molecules achieve therapeutic levels efficiently and consistently.

Controlled and Targeted Drug Delivery Systems
For drugs requiring sustained release or site-specific targeting, we develop intelligent delivery systems using polymers, microspheres, and liposomal encapsulation. These technologies allow for precise pharmacokinetic control, minimizing dose frequency and improving patient adherence. Our expertise in controlled-release design reduces side effects and enhances efficacy, especially in chronic or complex treatment regimens.

Excipient Selection and Compatibility Optimization
Excipients play a vital role in determining a formulation’s stability, manufacturability, and performance. We conduct rigorous compatibility studies, evaluating interactions between active pharmaceutical ingredients (APIs) and excipients under various conditions. Our scientists select and optimize excipient systems—binders, disintegrants, surfactants, and stabilizers—based on formulation goals, regulatory standards, and intended delivery route.

Comprehensive Pre-Formulation & Prototype Development
Before advancing to full development, we conduct detailed pre-formulation studies to characterize physicochemical properties such as pH, solubility, polymorphism, and hygroscopicity. These insights inform robust prototype formulation design, which is further refined through iterative testing and optimization. This foundational step is essential in mitigating downstream manufacturing risks and ensuring regulatory alignment.

Stability Testing and Clinical Trial Readiness
Our formulation development services also encompass ICH-compliant stability testing under real-time, accelerated, and stress conditions. This allows us to define shelf life, packaging requirements, and storage conditions. Each formulation is validated for scalability and readiness for GMP manufacturing, ensuring a smooth transition from the laboratory bench to the clinical trial supply chain.

Client-Centric Approach
We collaborate closely with pharmaceutical and biotech partners to customize formulation strategies aligned with clinical goals and commercial timelines. With a strong focus on scientific rigor and operational flexibility, Abiozen empowers clients to confidently advance their drug candidates through the development pipeline and into the marketplace.